https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51358 Wed 28 Feb 2024 16:08:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17052 2=0.38, P<0.0006), whereas mucositis was predicted by age, TL and PLR (R²=0.34, P<0.001). For the weekly schedule diarrhoea predominated (16%), with female gender as the only predictive factor. Although measures of uracil metabolism correlated well with 5FU metabolism (r=0.45–0.49), they did not indicate abnormal pyrimidine metabolism in this cohort and not surprisingly failed to predict for 5FU toxicity. Conclusion: Short TL of PBMNC and an increased PLR were strong predictors of mucositis and haematological toxicity in CRC patients undergoing 5FU treatment in the adjuvant setting.]]> Wed 11 Apr 2018 14:25:46 AEST ]]>